Bupleurum chinense Roots: a Bioactivity-Guided Approach toward Saponin-Type NF-κB Inhibitors
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چکیده
منابع مشابه
Bupleurum chinense Roots: a Bioactivity-Guided Approach toward Saponin-Type NF-κB Inhibitors.
The roots of Bupleurum chinense have a long history in traditional medicine to treat infectious diseases and inflammatory disorders. Two major compounds, saikosaponins A and D, were reported to exert potent anti-inflammatory activity by inhibiting NF-κB. In the present study, we isolated new saikosaponin analogues from the roots of B. chinese interfering with NF-κB activity in vitro. The methan...
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Chaihu, prepared from the dried roots of Bupleurum Chinense DC (also known as bei Chaihu in Chinese) or Bupleurum scorzoneraefolium WILD (also known as nan Chaihu in Chinese), is a herbal medicine for harmonizing and soothing gan (liver) qi stagnation. Substantial pharmacological studies have been conducted on Chaihu and its active components (saikosaponins). One of the active components of Cha...
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متن کاملcaffeic acid derivatives from bupleurum chinense
in this study, caffeic acid (ca) and its three derivatives including 3-caffeoylquinic acid (3-cqa, neochlorogenic acid), 4-caffeoylquinic acid (4-cqa, cryptochlorogenic acid), and 5-caffeoylquinic acid (5-cqa, chlorogenic acid) were identified in bupleurum chinense aerial parts using reverse-phase high-performance liquid chromatography (rp-hplc) with photodiode array (pda) detector, reference c...
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ژورنال
عنوان ژورنال: Planta Medica
سال: 2017
ISSN: 0032-0943,1439-0221
DOI: 10.1055/s-0043-118226